Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27497571 | 0.81 | LMNA (0.48) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL866289 | 0.79 | LMNA (0.53) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL27731125 | 0.78 | LMNA (0.57) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL28285589 | 0.76 | LMNA (0.55) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL1231766 | 0.76 | LMNA (0.55) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL1284277 | 0.75 | LMNA (0.53) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL28043565 | 0.75 | LMNA (0.53) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL10532645 | 0.75 | LMNA (0.53) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL4534739 | 0.74 | LMNA (0.48) | LMNAMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL205421 | 0.74 | LMNA (0.48) | LMNAMAPTKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |