Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10651230 | 0.89 | GRIA4 (0.51) | GRIA4GRIA2KMT2AKDM4ENPSR1 | |
| SCHEMBL5758052 | 0.78 | GRIA4 (0.64) | GRIA4GRIA2KMT2AKDM4EFNTA | |
| SCHEMBL10655092 | 0.77 | GRIA4 (0.41) | GRIA4GRIA2KMT2AKDM4ENPSR1 | |
| SCHEMBL10654112 | 0.76 | GRIA4 (0.61) | GRIA4GRIA2KMT2AKDM4ENPSR1 | |
| SCHEMBL10654301 | 0.72 | CTSS (0.42) | GRIA4GRIA2KMT2AKDM4ENPSR1 | |
| SCHEMBL16792125 | 0.71 | GRIA4 (0.78) | GRIA4GRIA2KMT2AFNTAFNTB | |
| SCHEMBL5756967 | 0.71 | GRIA4 (0.62) | GRIA4GRIA2KMT2AKDM4EMAPK1 | |
| SCHEMBL10655972 | 0.70 | GRIA4 (0.41) | GRIA4GRIA2KMT2AKDM4ENPSR1 | |
| SCHEMBL10652865 | 0.70 | GRIA4 (0.60) | GRIA4GRIA2KMT2ANPSR1L3MBTL1 | |
| SCHEMBL10655979 | 0.70 | GRIA4 (0.34) | GRIA4GRIA2KDM4ENPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |