Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.51 |
| ▸ | FNTA | P49354 | 11/20 | 0.50 |
| ▸ | FNTB | P49356 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653103 | 0.89 | GRIA4 (0.50) | GRIA4FNTAFNTBKDM4EKMT2A | |
| SCHEMBL5756967 | 0.81 | GRIA4 (0.62) | GRIA4FNTAFNTBKDM4EKMT2A | |
| SCHEMBL16792125 | 0.81 | GRIA4 (0.78) | GRIA4FNTAFNTBKMT2AGRIA2 | |
| SCHEMBL10655092 | 0.81 | GRIA4 (0.41) | GRIA4FNTAFNTBKDM4EKMT2A | |
| SCHEMBL10652865 | 0.79 | GRIA4 (0.60) | GRIA4FNTAFNTBKMT2AMAPT | |
| SCHEMBL10654301 | 0.74 | CTSS (0.42) | GRIA4FNTAFNTBKDM4EKMT2A | |
| SCHEMBL10651925 | 0.73 | GRIA2 (0.50) | GRIA4FNTAFNTBKDM4EKMT2A | |
| SCHEMBL10655134 | 0.72 | KDM4E (0.43) | GRIA4FNTAFNTBKDM4EKMT2A | |
| SCHEMBL10655972 | 0.71 | GRIA4 (0.41) | GRIA4KDM4EKMT2AMAPK1MAPT | |
| SCHEMBL13991798 | 0.70 | ALDH1A1 (0.47) | GRIA4FNTAFNTBKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273602-A1 | 3-Cyano-4-arylthiophenes | ELI LILLY AND COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |