Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410050 | 1.00 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL16549641 | 0.93 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL21428687 | 0.89 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL4818138 | 0.89 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL4341894 | 0.87 | NOTUM (0.78) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL19979604 | 0.86 | KDM4E (0.70) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL6850578 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL6871245 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL24784704 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL7028415 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1MAPK1NOTUMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | claimed |
| US-4539161-A | OPTICAL BRIGHTNERS, FLUORESCENT DYES | CIBA-GEIGY CORPORATION (US) | 1985-09-03 | — | — | US | disclosed |
| US-4263431-A | ARYL QUATERNARY AMINE PHOSPHONATE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |