Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410050 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL10653293 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL4341894 | 0.85 | NOTUM (0.78) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL13221930 | 0.82 | ALDH1A1 (0.68) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL98459 | 0.82 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL4818138 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL16549641 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL21428687 | 0.79 | KDM4E (0.64) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL29035962 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1MAPK1NOTUMHDAC4 | |
| SCHEMBL27725316 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1MAPK1NOTUMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570122-B2 | Compounds with anti-tumoral activity | AB SCIENCE (FR) | 2020-02-25 | — | — | US | disclosed |
| US-20180079747-A1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | AB SCIENCE (FR) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570122-B2 | Compounds with anti-tumoral activity | MKI67, GZMB, RB1 | KDM4E 2943/4885ALDH1A1 311/4885MAPK1 1810/4885 |
| US-20180079747-A1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | MKI67, TP53, VHL | KDM4E 3130/4885ALDH1A1 318/4885MAPK1 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.