Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.48 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654808 | 0.84 | ACE (0.66) | ACEPREPFAPACE2TSHR | |
| SCHEMBL22811097 | 0.80 | ALDH1A1 (0.49) | ACEPREPFAPACE2LMNA | |
| SCHEMBL10657887 | 0.79 | ACE (0.56) | ACEPREPFAPACE2LMNA | |
| SCHEMBL3472327 | 0.79 | ACE (0.71) | ACEPREPFAPACE2TSHR | |
| SCHEMBL11435575 | 0.79 | ACE (0.71) | ACEPREPFAPACE2TSHR | |
| SCHEMBL29749309 | 0.79 | ACE (0.71) | ACEPREPFAPACE2TSHR | |
| SCHEMBL10654820 | 0.78 | ACE (0.49) | ACEPREPFAPACE2LMNA | |
| SCHEMBL10656412 | 0.78 | ACE (0.58) | ACEACE2LMNA | |
| SCHEMBL10656626 | 0.78 | ACE (0.52) | ACEPREPFAPACE2LMNA | |
| SCHEMBL10976266 | 0.77 | ACE (0.78) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |