Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654873 | 0.88 | CYP1A2 (0.47) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL5573011 | 0.84 | CYP1A2 (0.46) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL18095949 | 0.80 | CYP1A2 (0.46) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL3496977 | 0.79 | GAA (0.52) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL9685398 | 0.78 | GAA (0.52) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL1935858 | 0.78 | CA12 (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL13422016 | 0.78 | KMT2A (0.57) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL10296020 | 0.78 | KMT2A (0.52) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL22206980 | 0.77 | GAA (0.45) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL66021 | 0.76 | ALDH1A1 (0.54) | GAAMGAMSIMGAM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126654-B1 | TETRAHYDROISOXAZOLO(4,5-C)PYRIDINE DERIVATIVES AND PREPARATION THEREOF | H. LUNDBECK A/S (DK) | 1988-05-04 | — | — | EP | disclosed |
| EP-0126654-A1 | Tetrahydroisoxazolo(4,5-c)pyridine derivatives and preparation thereof | H. LUNDBECK A/S (DK) | 1984-11-28 | — | — | EP | disclosed |
| US-3989707-A | NEUROLEPTIC AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-02 | — | — | US | disclosed |