Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391000 | 0.91 | KDM4E (0.76) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL5752305 | 0.91 | KDM4E (0.76) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9633158 | 0.90 | KDM4E (0.75) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL10651908 | 0.90 | KDM4E (0.75) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10884810 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10653754 | 0.88 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL10875284 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10915570 | 0.86 | ALDH1A1 (0.80) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9685581 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL11023756 | 0.85 | ALDH1A1 (0.79) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140116-B1 | A 6-FLUORO-1,4-DIHYDRO-4-OXO-7-SUBSTITUTED PIPERAZINYL-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AND THE METHOD FOR PREPARING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1988-05-25 | — | — | EP | claimed |
| US-4528287-A | 6-Fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinylquinoline-3-carboxylic acids and the method for preparing the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1985-07-09 | — | — | US | claimed |
| EP-0140116-A1 | A 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyl-quinoline-3-carboxylic acid derivative and the method for preparing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1985-05-08 | — | — | EP | claimed |
| EP-0140116-B1 | A 6-FLUORO-1,4-DIHYDRO-4-OXO-7-SUBSTITUTED PIPERAZINYL-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AND THE METHOD FOR PREPARING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1988-05-25 | — | — | EP | disclosed |
| US-4528287-A | 6-Fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinylquinoline-3-carboxylic acids and the method for preparing the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| EP-0140116-A1 | A 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyl-quinoline-3-carboxylic acid derivative and the method for preparing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1985-05-08 | — | — | EP | disclosed |