Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10656732 | 0.91 | KDM4E (0.60) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10653752 | 0.88 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10915571 | 0.88 | KDM4E (0.62) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10808537 | 0.84 | KDM4E (0.59) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL7809358 | 0.84 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10658597 | 0.84 | KDM4E (0.66) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL8899520 | 0.83 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10954347 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL9046101 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL2858133 | 0.80 | KDM4E (0.77) | ALDH1A1KDM4EHPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0140116-B1 | A 6-FLUORO-1,4-DIHYDRO-4-OXO-7-SUBSTITUTED PIPERAZINYL-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AND THE METHOD FOR PREPARING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1988-05-25 | — | — | EP | claimed |