SCHEMBL10653785

SCHEMBL10653785

CCCCN/C(C)=C\C(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.47
NPSR1 Q6W5P4 1/20 0.44
EPHX1 P07099 2/20 0.41
FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10665052 1.00 ACHE (0.47) ACHENPSR1EPHX1FAAH
SCHEMBL14148321 0.93 FAAH (0.50) ACHEEPHX1FAAH
SCHEMBL8047293 0.93 FAAH (0.50) ACHEEPHX1FAAH
SCHEMBL1275793 0.93 FAAH (0.50) ACHEEPHX1FAAH
SCHEMBL8025931 0.93 FAAH (0.50) ACHEEPHX1FAAH
SCHEMBL4625428 0.93 FAAH (0.50) ACHEEPHX1FAAH
SCHEMBL11345963 0.93 NPSR1 (0.47) ACHENPSR1EPHX1FAAH
SCHEMBL1972528 0.89 NPSR1 (0.47) ACHENPSR1EPHX1
SCHEMBL1972526 0.89 NPSR1 (0.47) ACHENPSR1EPHX1
SCHEMBL1972523 0.89 NPSR1 (0.47) ACHENPSR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9840599-B2 Process for curing thermoset resins AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2017-12-12 US disclosed
US-9840599-B2 Process for curing thermoset resins AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2017-12-12 US disclosed
US-20150225515-A1 Process For Curing Thermoset Resins AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-08-13 US disclosed
US-20150225515-A1 Process For Curing Thermoset Resins AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-08-13 US disclosed
EP-0160256-B1 CONDENSED FURANONES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE BAYER AG (DE) 1988-09-28 EP disclosed
US-4762853-A 1-oxo-1,3,4,7-tetrahydrobenzo[C]furans BAYER AKTIENGESELLSCHAFT (DE) 1988-08-09 US disclosed
US-4668691-A Circulation-active novel 7-aryl-or pyridyl-1-oxo-1,c,4,7-tetrahydrobenzofurans BAYER AKTIENGESELLSCHAFT (DE) 1987-05-26 US disclosed
US-4622332-A Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity BAYER AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed
EP-0088276-B1 COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL PREPARATIONS BAYER AG (DE) 1986-04-30 EP disclosed
EP-0160256-A2 Condensed furanones, process for their preparation and their pharmaceutical use BAYER AG (DE) 1985-11-06 EP disclosed
EP-0088276-A1 Compounds, process for their preparation and their use as pharmaceutical preparations BAYER AG (DE) 1983-09-14 EP disclosed