Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269012 | 0.76 | KDM4E (0.64) | HTTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28344828 | 0.73 | GRIN2D (0.48) | HTTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29805854 | 0.73 | CHUK (0.55) | ALDH1A1KDM4EHSD17B10GRIN2DGRIN3B | |
| SCHEMBL28521666 | 0.73 | CHUK (0.55) | ALDH1A1KDM4EHSD17B10GRIN2DGRIN3B | |
| SCHEMBL25989272 | 0.71 | MEN1 (0.39) | HTTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6579538 | 0.70 | GRIN2D (0.53) | HTTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3223994 | 0.70 | LMNA (0.66) | MEN1KMT2AALDH1A1KDM4EGRIN2D | |
| SCHEMBL3423565 | 0.69 | KDM4E (0.50) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13412888 | 0.68 | GRIN1 (0.48) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9387679 | 0.68 | GRIN2D (0.50) | HTTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0101330-B1 | 2-QUINOLONE DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1988-08-24 | — | — | EP | disclosed |
| US-4526894-A | Antiinflammatory agents | NIPPON SHINYAKU CO. LTD. (JP) | 1985-07-02 | — | — | US | disclosed |
| EP-0101330-A2 | 2-Quinolone derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1984-02-22 | — | — | EP | disclosed |