SCHEMBL10654093

SCHEMBL10654093

OCC1(C(O)Cc2ccc(F)c(Oc3ccccc3)c2)CCCC1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.37
LPAR1 Q92633 4/20 0.33
LPAR5 Q9H1C0 4/20 0.33
LTA4H P09960 1/20 0.33
SRD5A2 P31213 1/20 0.33
FFAR4 Q5NUL3 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10655521 0.74 FFAR4 (0.36) TTRLPAR1LPAR5FFAR4
SCHEMBL10654089 0.74 FFAR4 (0.38) TTRLTA4HFFAR4
SCHEMBL9539557 0.74 TTR (0.65) TTRLPAR1LPAR5LTA4H
SCHEMBL11091466 0.73 TTR (0.39) TTRLPAR1LPAR5LTA4HSRD5A2
SCHEMBL11091463 0.73 TTR (0.39) TTRLPAR1LPAR5LTA4HSRD5A2
Hydrochloric Acid SCHEMBL10469327 0.72 TTR (0.63) TTRLPAR1LPAR5LTA4H
SCHEMBL9682176 0.71 TTR (0.49) TTRLTA4HFFAR4
SCHEMBL10728858 0.71 PPARA (0.39) LPAR1LPAR5
SCHEMBL9804282 0.69 TTR (0.46) TTRLPAR1LPAR5LTA4H
SCHEMBL27294732 0.68 TTR (0.38) TTRLPAR1LPAR5SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0266891-A1 Insecticidal ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP disclosed