Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804282 | 0.91 | TTR (0.46) | TTRLTA4HPOLB | |
| SCHEMBL9539557 | 0.87 | TTR (0.65) | TTRCYP4F2CYP4A11LTA4H | |
| Hydrochloric Acid SCHEMBL10469327 | 0.85 | TTR (0.63) | TTRCYP4F2CYP4A11LTA4H | |
| SCHEMBL11166948 | 0.84 | LPAR1 (0.42) | TTRHRH1FFAR4 | |
| SCHEMBL4342229 | 0.84 | TTR (0.42) | TTRLTA4HPOLBHRH1F2 | |
| SCHEMBL14406381 | 0.84 | TTR (0.45) | TTRHRH1 | |
| SCHEMBL9681679 | 0.84 | TDP1 (0.42) | TTRTDP1POLBHRH1F2 | |
| SCHEMBL28480212 | 0.83 | FFAR1 (0.62) | TDP1FFAR4 | |
| SCHEMBL8567112 | 0.81 | TTR (0.40) | TTRPOLBHRH1 | |
| SCHEMBL10335055 | 0.81 | TTR (0.40) | TTRPOLBHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091416-A | INSECTICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0361695-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | disclosed |
| US-4833163-A | INSECTICIDES, NEMATOCIDES, MITICIDES | ROUSSEL UCLAF (FR) | 1989-05-23 | — | — | US | disclosed |
| EP-0082049-A2 | Ethers with chiral atoms in the organic rest groups, their preparation, their use in the resolution of alcohols or of certain hemiacetals, and compounds so resolved | ROUSSEL-UCLAF (FR) | 1983-06-22 | — | — | EP | disclosed |