Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682176 | 0.91 | TTR (0.49) | TTRLTA4HPOLB | |
| SCHEMBL10335055 | 0.85 | TTR (0.40) | TTRLPAR1LPAR5POLB | |
| SCHEMBL8567112 | 0.85 | TTR (0.40) | TTRLPAR1LPAR5POLB | |
| SCHEMBL9539557 | 0.84 | TTR (0.65) | TTRLTA4HLPAR1LPAR5 | |
| SCHEMBL10446712 | 0.84 | PPARG (0.45) | LPAR1LPAR5 | |
| SCHEMBL2914006 | 0.83 | F2 (0.56) | TTRLTA4HEPHX2POLB | |
| Hydrochloric Acid SCHEMBL10469327 | 0.83 | TTR (0.63) | TTRLTA4HLPAR1LPAR5 | |
| SCHEMBL8638059 | 0.82 | TTR (0.44) | TTRLPAR1LPAR5 | |
| SCHEMBL11166948 | 0.81 | LPAR1 (0.42) | TTRLPAR1LPAR5 | |
| SCHEMBL14406381 | 0.81 | TTR (0.45) | TTRLPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4883789-A | Substituted phenyltrialkylsilane insecticides | FMC CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| US-4709068-A | NONTOXIC TO FISH | FMC CORPORATION (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |