Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654587 | 0.81 | HDAC3 (0.46) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL10652757 | 0.81 | ACP3 (0.41) | MEN1KMT2APARP1 | |
| SCHEMBL16559376 | 0.72 | HDAC4 (0.62) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL10652795 | 0.71 | LMNA (0.40) | CES2CES1CNR2MEN1KMT2A | |
| SCHEMBL11279827 | 0.70 | CES2 (0.68) | HDAC4HDAC7HDAC5IGFBP3CES2 | |
| SCHEMBL4536216 | 0.69 | HDAC4 (1.00) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL7395276 | 0.68 | HDAC4 (0.53) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL23032354 | 0.68 | HDAC4 (0.57) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL16559374 | 0.68 | HDAC4 (0.57) | HDAC4HDAC7HDAC5CES2CES1 | |
| SCHEMBL28226456 | 0.68 | HDAC4 (0.53) | HDAC4HDAC7HDAC5CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267155-A2 | Bicyclic compounds | Zyma SA (CH) | 1988-05-11 | — | — | EP | disclosed |