Methanesulfonamide

Methanesulfonamide

SCHEMBL10655700

CCN(CC)c1ccc(N)cc1.CS(N)(=O)=O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.76
L3MBTL1 Q9Y468 3/20 0.76
CYP3A4 P08684 2/20 0.76
MAPK1 P28482 2/20 0.76
TDP1 Q9NUW8 2/20 0.76
PSMD14 O00487 1/20 0.76
TSHR P16473 1/20 0.76
RECQL P46063 1/20 0.76
GFER P55789 1/20 0.76
MEN1 O00255 2/20 0.49
HPGD P15428 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.49
HSP90AA1 P07900 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
ALDH3A1 P30838 1/20 0.48
ALDH1A3 P47895 1/20 0.48
ESRRG P62508 1/20 0.46
S100B P04271 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL1304807 0.88 ALDH1A1 (0.76) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
SCHEMBL33781 0.87 ALDH1A1 (1.00) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
SCHEMBL8467252 0.87 ALDH1A1 (1.00) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Sulfuric Acid SCHEMBL11787283 0.86 ALDH1A1 (0.73) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Hydrochloric Acid SCHEMBL970321 0.85 ALDH1A1 (0.95) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Hydrochloric Acid SCHEMBL970320 0.85 ALDH1A1 (0.95) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Methanesulfonamide SCHEMBL10825984 0.85 ALDH1A1 (0.55) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Thiosulfuric Acid SCHEMBL31265589 0.85 ALDH1A1 (0.70) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Sulfuric Acid SCHEMBL28552343 0.85 ALDH1A1 (0.70) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1
Sulfur Dioxide SCHEMBL6515046 0.83 ALDH1A1 (0.83) ALDH1A1L3MBTL1CYP3A4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0143570-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1988-01-27 EP disclosed
US-4566875-A HAIR DYES L'OREAL (FR) 1986-01-28 US disclosed
US-4149848-A N-/TETRAHYDROFURFURYL/P-PHENYLENEDIAMINES L'OREAL (FR) 1979-04-17 US disclosed