Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL11688459 | 0.88 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Dioxane SCHEMBL11236226 | 0.88 | FFAR3 (0.50) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28122017 | 0.87 | EGLN1 (0.53) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Valeric Acid SCHEMBL27832145 | 0.86 | AKR1B1 (0.58) | TSHRAKR1B1GPR84PPARGPPARD | |
| Hexanoate SCHEMBL5547721 | 0.84 | AKR1B1 (0.70) | TSHRAKR1B1GPR84PPARGPPARD | |
| Butyric Acid SCHEMBL1007031 | 0.84 | FFAR3 (0.81) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Behenic Acid SCHEMBL27765902 | 0.82 | GPR84 (0.71) | TSHRAKR1B1GPR84PPARGPPARD | |
| Butyric Acid SCHEMBL203760 | 0.81 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL10338134 | 0.81 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL1257810 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107115340-A | A kind of antituberculotic and its production and use | 浙江大学 | 2017-09-01 | — | — | CN | disclosed |
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |
| EP-0165033-A2 | Conformationally restricted thymopentin-like compounds | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4547489-A | OLIGOPEPTIDE HAVING IMMUNOREGULATORY ACTIVITY | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
| US-4272525-A | FUNGICIDES | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-3956260-A | ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |