Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 6/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10464433 | 0.87 | MAPK8 (0.57) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL10652966 | 0.86 | KDM4E (0.51) | MAPK8KDM4EMAPTHPGD | |
| SCHEMBL27286578 | 0.85 | MAPK8 (0.55) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL10761739 | 0.85 | MAPK8 (0.52) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL9538497 | 0.84 | MAPK8 (0.55) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL9536815 | 0.80 | MAPK8 (0.51) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL9537285 | 0.77 | MAPK8 (0.56) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL8140517 | 0.76 | PSEN1 (0.62) | KDM4E | |
| SCHEMBL13465314 | 0.76 | MAPK8 (0.55) | MAPK8NR4A2PKMMAPK9PLA2G2A | |
| SCHEMBL28116309 | 0.76 | ALDH1A1 (0.56) | MAPK8NR4A2PKMMAPK9PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092380-B1 | ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4596814-A | Antiallergens | WARNER-LAMBERT COMPANY (US) | 1986-06-24 | — | — | US | disclosed |
| US-4503236-A | Antiallergic 4Hfuro[3,2-b]indoles | WARNER-LAMBERT COMPANY (US) | 1985-03-05 | — | — | US | disclosed |
| EP-0092380-A2 | Antiallergic 4H-furo(3,2-b)indoles and their production | WARNER-LAMBERT COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |