Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 6/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656119 | 1.00 | LMNA (0.58) | LMNASMN1; SMN2NR4A2PDE4DNR1I2 | |
| SCHEMBL10656140 | 1.00 | LMNA (0.58) | LMNASMN1; SMN2NR4A2PDE4DNR1I2 | |
| SCHEMBL10661806 | 0.86 | PDE4D (0.59) | NR4A2PDE4DNR1I2HMGCRCYP2C9 | |
| SCHEMBL10661859 | 0.86 | PDE4D (0.59) | NR4A2PDE4DNR1I2HMGCRCYP2C9 | |
| SCHEMBL10661853 | 0.86 | PDE4D (0.59) | NR4A2PDE4DNR1I2HMGCRCYP2C9 | |
| SCHEMBL10656133 | 0.86 | PDE4D (0.59) | NR4A2PDE4DNR1I2HMGCRCYP2C9 | |
| SCHEMBL10659561 | 0.80 | LMNA (0.64) | LMNASMN1; SMN2KDM4EFABP3FABP4 | |
| SCHEMBL10659554 | 0.80 | LMNA (0.64) | LMNASMN1; SMN2KDM4EFABP3FABP4 | |
| SCHEMBL10658955 | 0.78 | LMNA (0.60) | LMNASMN1; SMN2KDM4EFABP3FABP4 | |
| SCHEMBL10658971 | 0.78 | LMNA (0.60) | LMNASMN1; SMN2KDM4EFABP3FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761419-A | ANTILIPEMIC | WARNER-LAMBERT COMPANY (US) | 1988-08-02 | — | — | US | disclosed |