Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658955 | 1.00 | LMNA (0.60) | LMNASMN1; SMN2FABP3FABP4PDE2A | |
| SCHEMBL10657576 | 0.90 | LMNA (0.64) | LMNASMN1; SMN2FABP3FABP4PDE2A | |
| SCHEMBL10659561 | 0.87 | LMNA (0.64) | LMNASMN1; SMN2FABP3FABP4PDE2A | |
| SCHEMBL10659554 | 0.87 | LMNA (0.64) | LMNASMN1; SMN2FABP3FABP4PDE2A | |
| SCHEMBL10661744 | 0.81 | FABP3 (0.47) | LMNASMN1; SMN2FABP3FABP4KDM4E | |
| SCHEMBL10658967 | 0.81 | FABP3 (0.47) | LMNASMN1; SMN2FABP3FABP4KDM4E | |
| SCHEMBL10656128 | 0.78 | LMNA (0.58) | LMNASMN1; SMN2FABP3FABP4KDM4E | |
| SCHEMBL10656119 | 0.78 | LMNA (0.58) | LMNASMN1; SMN2FABP3FABP4KDM4E | |
| SCHEMBL10656140 | 0.78 | LMNA (0.58) | LMNASMN1; SMN2FABP3FABP4KDM4E | |
| SCHEMBL3316451 | 0.73 | LMNA (0.66) | LMNASMN1; SMN2FABP3FABP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761419-A | ANTILIPEMIC | WARNER-LAMBERT COMPANY (US) | 1988-08-02 | — | — | US | disclosed |