Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10664905 | 0.80 | MAOB (0.48) | ALOX5GGPS1CACNA1B | |
| SCHEMBL10636289 | 0.80 | GPBAR1 (0.68) | MAPK1GPBAR1CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL11046795 | 0.79 | MAOB (0.47) | GGPS1PPARACACNA1B | |
| SCHEMBL10656148 | 0.77 | ALOX5 (0.39) | TDP1GPBAR1CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL9576090 | 0.77 | KDM4E (0.63) | KDM4EMAPK1TDP1GPBAR1CYSLTR2 | |
| SCHEMBL29666114 | 0.77 | TDP1 (0.68) | KDM4EMAPK1TDP1GPBAR1CYSLTR2 | |
| SCHEMBL470925 | 0.77 | TDP1 (0.68) | KDM4EMAPK1TDP1GPBAR1CYSLTR2 | |
| SCHEMBL10635136 | 0.76 | GPBAR1 (0.43) | MAPK1GPBAR1CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL10854965 | 0.76 | MAOB (0.49) | ALOX5CACNA1B | |
| SCHEMBL5374714 | 0.75 | KDM4E (0.61) | KDM4EMAPK1TDP1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |