Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10656156 | 0.77 | KDM4E (0.46) | ALOX5GPBAR1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL10664905 | 0.77 | MAOB (0.48) | ALOX5 | |
| SCHEMBL10636289 | 0.76 | GPBAR1 (0.68) | ALOX5GPBAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11046795 | 0.76 | MAOB (0.47) | — | |
| SCHEMBL10635136 | 0.76 | GPBAR1 (0.43) | ALOX5GPBAR1PARP10MEN1KMT2A | |
| SCHEMBL10854965 | 0.73 | MAOB (0.49) | ALOX5 | |
| SCHEMBL9289234 | 0.69 | NCEH1 (0.57) | MEN1KMT2ACNR1CNR2MAPT | |
| SCHEMBL10434695 | 0.68 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL28010488 | 0.68 | NCEH1 (0.56) | MEN1KMT2ACNR1CNR2MAPT | |
| SCHEMBL10638628 | 0.67 | CYSLTR1 (0.60) | ALOX5GPBAR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | claimed |
| EP-0181568-A2 | Anti-inflammatory/anti-allergic compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1986-05-21 | — | — | EP | claimed |
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4778931-A | ENZYME INHIBITORS | USV PHARMACEUTICAL CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |