Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 5/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033435 | 0.87 | ALDH1A1 (0.47) | GPR17P2RY2FFAR4MEN1KMT2A | |
| SCHEMBL11518080 | 0.85 | FFAR4 (0.56) | GPR17FFAR4MEN1KMT2APOLB | |
| SCHEMBL11623279 | 0.85 | SMN1; SMN2 (0.53) | GPR17P2RY2FFAR4MEN1KMT2A | |
| SCHEMBL11628222 | 0.85 | TSHR (0.52) | GPR17P2RY2FFAR4MEN1KMT2A | |
| SCHEMBL11623604 | 0.85 | GPR17 (0.47) | GPR17P2RY2FFAR4MEN1KMT2A | |
| SCHEMBL10654918 | 0.85 | ALDH1A1 (0.45) | GPR17FFAR4MEN1KMT2APOLB | |
| SCHEMBL10786727 | 0.84 | GPR17 (0.50) | GPR17FFAR4MEN1KMT2APOLB | |
| SCHEMBL11628567 | 0.84 | GPR17 (0.48) | GPR17FFAR4MEN1KMT2APOLB | |
| SCHEMBL11089561 | 0.83 | GPR17 (0.43) | GPR17P2RY2ALDH1A1LMNATDP1 | |
| SCHEMBL11851786 | 0.82 | ALPL (0.48) | GPR17P2RY2FFAR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115039-B1 | SUBSTITUTED PHENYLSULFONYLOXYBENZIMIDAZOLE CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-02-10 | — | — | EP | disclosed |
| US-4639463-A | Substituted phenylsulfonyloxybenzimidazolecarbamates and anthelmintic compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0115039-A1 | Substituted phenylsulfonyloxybenzimidazole carbamates, process for their preparation and their application as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |