SCHEMBL10656330

SCHEMBL10656330

O=c1[nH]c2ccccc2c(=O)n1CCCCCn1ccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.73
QPCT Q16769 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10750586 0.99 KMT2A (0.74) KMT2AQPCT
SCHEMBL10653074 0.96 KMT2A (0.78) KMT2AQPCT
SCHEMBL10755231 0.85 ALDH1A1 (0.60)
SCHEMBL5131585 0.84 QPCT (1.00) KMT2AQPCT
SCHEMBL10660769 0.82
SCHEMBL10654636 0.82
SCHEMBL10660798 0.82 TBXAS1 (0.69)
SCHEMBL10756182 0.82 ALDH1A1 (0.63) KMT2AQPCT
SCHEMBL10755359 0.82 KDM4E (0.60)
SCHEMBL10655198 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0293500-A1 3-heteroalkyl-2,4.quinzaoline-diones AMERICAN CYANAMID COMPANY (US) 1988-12-07 EP disclosed
US-4684654-A THROMBOXANE SYNTHETASE INHIBITORS, HYPOTENSIVES AMERICAN CYANAMID COMPANY (US) 1987-08-04 US disclosed