Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PIEZO1 | Q92508 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5436712 | 0.85 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL29594772 | 0.83 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL10050765 | 0.83 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL271188 | 0.83 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL5500906 | 0.83 | IDO1 (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL146337 | 0.83 | SLC6A4 (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL5500903 | 0.83 | ALDH1A1 (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL6152782 | 0.83 | IDO1 (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL5235367 | 0.83 | ALDH1A1 (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A | |
| SCHEMBL856434 | 0.83 | PNMT (0.43) | SLC6A4HTR2AKCNH2SLC6A2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792635-A | Symmetric benzophenones substituted by groups containing fluorine | BAYER AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0156278-B1 | PROCESS FOR THE PREPARATION OF SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS, THEIR USE AND SYMMETRICAL BENZOPHENONES SUBSTITUTED BY FLUOR-CONTAINING GROUPS | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |
| EP-0156278-A2 | Process for the preparation of symmetrical benzophenones substituted by fluor-containing groups, their use and symmetrical benzophenones substituted by fluor-containing groups | BAYER AG (DE) | 1985-10-02 | — | — | EP | disclosed |