Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2527429 | 1.00 | THRB (0.38) | THRBFNTAFNTBGBA1 | |
| SCHEMBL3972790 | 0.98 | THRB (0.35) | THRBFNTAFNTBGBA1 | |
| SCHEMBL718913 | 0.89 | THRB (0.37) | THRBGBA1 | |
| SCHEMBL719147 | 0.87 | THRB (0.34) | THRB | |
| SCHEMBL719148 | 0.87 | THRB (0.34) | THRB | |
| SCHEMBL4942932 | 0.83 | THRB (0.41) | THRBFNTAFNTB | |
| SCHEMBL2524427 | 0.82 | THRB (0.41) | THRBGBA1 | |
| SCHEMBL2522478 | 0.82 | THRB (0.41) | THRBGBA1 | |
| SCHEMBL2522485 | 0.82 | THRB (0.41) | THRBGBA1 | |
| SCHEMBL3963084 | 0.80 | THRB (0.38) | THRBGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743667-A | ACRYLATED SILOXXANES, OXYGEN PERMEABLE | NIPPON CONTACT LENS, INC. (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |