Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886709 | 0.93 | THRB (0.34) | THRBFNTAFNTB | |
| SCHEMBL6053879 | 0.85 | FNTA (0.34) | FNTAFNTB | |
| SCHEMBL10656366 | 0.83 | THRB (0.38) | THRBFNTAFNTB | |
| SCHEMBL2527429 | 0.83 | THRB (0.38) | THRBFNTAFNTB | |
| SCHEMBL3972790 | 0.81 | THRB (0.35) | THRBFNTAFNTB | |
| SCHEMBL6130468 | 0.81 | THRB (0.44) | THRBCA2 | |
| SCHEMBL10661692 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL2405464 | 0.77 | FNTA (0.36) | FNTAFNTB | |
| SCHEMBL3858790 | 0.76 | THRB (0.48) | THRBCA2 | |
| SCHEMBL8618188 | 0.76 | THRB (0.48) | THRBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7344731-B2 | Rigid gas permeable lens material | BAUSCH & LOMB INCORPORATED (US) | 2008-03-18 | — | — | US | disclosed |
| US-20060276605-A1 | Rigid gas permeable lens material | BAUSCH & LOMB INCORPORATED | 2006-12-07 | — | — | US | disclosed |
| US-4743667-A | ACRYLATED SILOXXANES, OXYGEN PERMEABLE | NIPPON CONTACT LENS, INC. (JP) | 1988-05-10 | — | — | US | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |