Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654701 | 0.83 | DPP4 (0.38) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL10653648 | 0.80 | DPP4 (0.40) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL10657720 | 0.77 | GRIK1 (0.42) | NOS2NOS3NOS1 | |
| SCHEMBL10657241 | 0.77 | GRIK1 (0.42) | NOS2NOS3NOS1 | |
| SCHEMBL29569099 | 0.73 | DPP4 (0.61) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL31338627 | 0.73 | NOD1 (0.45) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL31031060 | 0.73 | DPP4 (0.61) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL2807373 | 0.73 | DPP4 (0.61) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL10625373 | 0.72 | DPP8 (0.50) | DPP4DPP8DPP9MMEACE | |
| SCHEMBL29499873 | 0.72 | DPP4 (0.59) | DPP4DPP8DPP9MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730006-A | BACTERICIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-08 | — | — | US | disclosed |