Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.42 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657720 | 1.00 | GRIK1 (0.42) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL10656395 | 0.77 | DPP4 (0.35) | NOS2NOS3NOS1 | |
| SCHEMBL10657081 | 0.75 | GSR (0.48) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL9635451 | 0.75 | BLM (0.59) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL10655332 | 0.75 | GSR (0.48) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL9635455 | 0.75 | BLM (0.59) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL8068164 | 0.73 | GSR (0.68) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL602426 | 0.73 | GSR (0.68) | GRIK1GRIK2GSRGRM8GRM6 | |
| SCHEMBL10659072 | 0.73 | BLM (0.35) | BLMKMT2APMP22SLC6A2SLC6A4 | |
| SCHEMBL25292030 | 0.72 | GSR (0.54) | GRIK1GRIK2GSRGRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4730006-A | BACTERICIDES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-03-08 | — | — | US | disclosed |