Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GLB1 | P16278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655874 | 1.00 | CRBN (0.41) | CRBNMMP2RPS6KA3ESR1ESR2 | |
| N4-Hydroxycytosine SCHEMBL13071713 | 0.72 | — | — | |
| N4-Hydroxycytosine SCHEMBL24574318 | 0.72 | — | — | |
| SCHEMBL10655304 | 0.70 | MAPT (0.39) | CRBNMMP2MEN1KMT2AMAPT | |
| SCHEMBL10655308 | 0.70 | MAPT (0.39) | CRBNMMP2MEN1KMT2AMAPT | |
| SCHEMBL11218738 | 0.68 | MEN1 (0.43) | ESR1ESR2S100BCA12CA1 | |
| SCHEMBL10653826 | 0.68 | CRBN (0.41) | CRBNMMP2MEN1KMT2AMAPT | |
| SCHEMBL10652272 | 0.67 | MEN1 (0.41) | CRBNMMP2MEN1KMT2AMAPT | |
| SCHEMBL10652269 | 0.67 | MEN1 (0.41) | CRBNMMP2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10651039 | 0.66 | MEN1 (0.40) | CRBNMMP2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |