Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652269 | 1.00 | MEN1 (0.41) | MEN1KMT2ACRBNMMP2GRIN2D | |
| Hydrochloric Acid SCHEMBL10651039 | 0.98 | MEN1 (0.40) | MEN1KMT2ACRBNMMP2GRIN2D | |
| Hydrochloric Acid SCHEMBL10651036 | 0.98 | MEN1 (0.40) | MEN1KMT2ACRBNMMP2GRIN2D | |
| SCHEMBL10653826 | 0.84 | CRBN (0.41) | MEN1KMT2ACRBNMMP2ATAD2 | |
| SCHEMBL10654025 | 0.71 | NQO2 (0.40) | CRBNMMP2HSD17B10LMNAALDH1A1 | |
| SCHEMBL10653786 | 0.68 | PTGS2 (0.42) | CRBNMMP2 | |
| N4-Hydroxycytosine SCHEMBL24574318 | 0.67 | — | — | |
| N4-Hydroxycytosine SCHEMBL13071713 | 0.67 | — | — | |
| SCHEMBL13030159 | 0.67 | CRBN (0.45) | CRBNMMP2 | |
| SCHEMBL10656570 | 0.67 | CRBN (0.41) | MEN1KMT2ACRBNMMP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123402-B1 | PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |