⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N4-Hydroxycytosine SCHEMBL13071713 | 1.00 | — | — | |
| SCHEMBL10656570 | 0.72 | CRBN (0.41) | — | |
| SCHEMBL10655874 | 0.72 | CRBN (0.41) | — | |
| SCHEMBL10653826 | 0.69 | CRBN (0.41) | — | |
| SCHEMBL10652269 | 0.67 | MEN1 (0.41) | — | |
| SCHEMBL10652272 | 0.67 | MEN1 (0.41) | — | |
| Uracil SCHEMBL3798527 | 0.67 | CRBN (1.00) | — | |
| Uracil SCHEMBL8235 | 0.67 | — | — | |
| Uracil SCHEMBL5089507 | 0.67 | — | — | |
| Uracil SCHEMBL11607890 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419110-A1 | TREATMENT OF VIRUSES WITH ANTIVIRAL NUCLEOSIDES | Merck Sharp & Dohme LLC (US) | 2024-08-28 | — | — | EP | claimed |
| WO-2023070058-A1 | TREATMENT OF VIRUSES WITH ANTIVIRAL NUCLEOSIDES | MERCK SHARP & DOHME LLC (US) | 2023-04-27 | — | — | WO | claimed |
| WO-2022140705-A1 | PRODRUGS OF PHARMACEUTICAL AGENTS | ALMARSSON ORN (US) | 2022-06-30 | — | — | WO | disclosed |