Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 6/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 4/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403621 | 0.86 | KLK7 (0.53) | TSHRACEFKBP1A | |
| SCHEMBL10658334 | 0.85 | ACE (0.46) | ACELMNAACE2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7264395 | 0.83 | FKBP1A (0.50) | ALDH1A1CYP3A4TSHRACEFKBP1A | |
| SCHEMBL7264291 | 0.82 | DPP8 (0.66) | ALDH1A1CYP3A4TSHRACEFKBP1A | |
| Hydrochloric Acid SCHEMBL10404195 | 0.82 | ACE (0.49) | TSHRACEFKBP1ADPP4DPP8 | |
| Hydrochloric Acid SCHEMBL7264261 | 0.81 | DPP8 (0.65) | ALDH1A1CYP3A4TSHRACEFKBP1A | |
| SCHEMBL10404990 | 0.80 | FKBP1A (0.50) | ALDH1A1ACEFKBP1ALMNA | |
| SCHEMBL6437871 | 0.80 | ACE (0.57) | ALDH1A1CYP3A4TSHRACEFKBP1A | |
| SCHEMBL7428633 | 0.80 | ACE (0.57) | ALDH1A1CYP3A4TSHRACEFKBP1A | |
| SCHEMBL1995962 | 0.80 | CYP3A4 (0.56) | ALDH1A1CYP3A4TSHRACEFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |
| EP-0173510-A2 | Tripeptide derivatives for use as anti-hypertensive agents | AJINOMOTO CO., INC. (JP) | 1986-03-05 | — | — | EP | disclosed |