SCHEMBL10656642

SCHEMBL10656642

CCc1ccc(CSCc2ccc(CC)c(CC)c2CC)c(CC)c1CC

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
CTRC Q99895 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11672598 0.86 GABRA1 (0.44) CYP1A2CYP2C9CYP2C19GABRA1GABRB2
SCHEMBL166573 0.84 GABRA1 (0.41) GABRA1GABRB2CTRC
SCHEMBL29619533 0.84 GABRA1 (0.41) GABRA1GABRB2CTRC
SCHEMBL6711531 0.81 GABRA1 (0.36) GABRA1GABRB2CTRC
Ammonia Solution, Strong SCHEMBL27539208 0.81 GABRA1 (0.39) GABRA1GABRB2CTRC
Ethylene SCHEMBL27502363 0.78 GABRA1 (0.38) GABRA1GABRB2CTRC
SCHEMBL7643316 0.74 GABRA1 (0.35) GABRA1GABRB2CTRC
SCHEMBL2773980 0.72 GABRA1 (0.33) GABRA1GABRB2CTRC
SCHEMBL4076418 0.72 NOS3 (0.40) CYP1A2CYP2C9CYP2C19CYP3A4GABRA1
SCHEMBL4077011 0.72 PRKCI (0.39) GABRA1GABRB2CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4783562-A Process for the preparation of trichloromethyl-substituted aromatic compounds, and trichloromethyl-substituted aromatic compounds obtained in this process BAYER AKTIENGESELLSCHAFT (DE) 1988-11-08 US disclosed