SCHEMBL1065669

SCHEMBL1065669

C=CC(=O)OC(C)[Si](OC)(OC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.36
HCAR2 Q8TDS4 1/20 0.36
AKT1 P31749 1/20 0.33
TSHR P16473 2/20 0.32
GSTO1 P78417 2/20 0.31
KMT2A Q03164 3/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
TGM2 P21980 1/20 0.31
THRA P10827 1/20 0.31
MAPT P10636 2/20 0.30
LMNA P02545 1/20 0.30
XBP1 P17861 1/20 0.30
ATM Q13315 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1066828 0.84 THRB (0.36) THRBHCAR2AKT1TSHRGSTO1
SCHEMBL1066701 0.82 THRB (0.38) THRBHCAR2TSHRGSTO1KMT2A
SCHEMBL1068329 0.81 THRB (0.36) THRBHCAR2AKT1TSHRGSTO1
SCHEMBL435743 0.78 MAPT (0.36) THRBHCAR2AKT1TSHRGSTO1
SCHEMBL11804355 0.74 THRB (0.36) THRBHCAR2AKT1TSHRGSTO1
SCHEMBL1066659 0.73 TSHR (0.37) THRBHCAR2TSHRTGM2MAPT
SCHEMBL10526785 0.73 THRB (0.35) THRBHCAR2TSHRKMT2ATHRA
SCHEMBL1065439 0.73 THRB (0.42) THRBHCAR2AKT1TSHRGSTO1
SCHEMBL8672651 0.72 THRB (0.36) THRBHCAR2AKT1TSHRGSTO1
SCHEMBL1066198 0.72 THRB (0.42) THRBHCAR2TSHRTGM2THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829142-B2 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2014-09-09 US disclosed
EP-2270070-B1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO LTD (JP) 2014-07-30 EP disclosed
EP-2565217-B1 Curable composition and process for production of organosilicon compound TOAGOSEI CO LTD (JP) 2014-05-14 EP disclosed
US-20130149455-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2013-06-13 US disclosed
EP-2565217-A1 Curable composition and process for production of organosilicon compound TOAGOSEI CO., LTD. (JP) 2013-03-06 EP disclosed
US-20110071255-A1 CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND TOAGOSEI CO., LTD. (JP) 2011-03-24 US disclosed
EP-2270070-A1 CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND Toagosei Co., Ltd (JP) 2011-01-05 EP disclosed