Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1066701 | 0.89 | THRB (0.38) | THRBTHRAGSTO1HCAR2TSHR | |
| SCHEMBL1067390 | 0.85 | THRB (0.35) | THRBTHRAGSTO1HCAR2MEN1 | |
| SCHEMBL1065669 | 0.84 | THRB (0.36) | THRBTHRAGSTO1HCAR2TSHR | |
| SCHEMBL1065011 | 0.77 | LMNA (0.37) | THRBGSTO1HCAR2TSHRACACB | |
| SCHEMBL8668330 | 0.77 | THRB (0.35) | THRBTHRAGSTO1HCAR2TSHR | |
| SCHEMBL10525599 | 0.76 | ALDH1A1 (0.34) | THRBTHRAGSTO1HCAR2TSHR | |
| SCHEMBL29146074 | 0.76 | MAPT (0.34) | THRBTHRAGSTO1HCAR2TSHR | |
| SCHEMBL1068329 | 0.75 | THRB (0.36) | THRBTHRAGSTO1HCAR2TSHR | |
| SCHEMBL1066198 | 0.75 | THRB (0.42) | THRBTHRAHCAR2TSHRMAPT | |
| SCHEMBL1063251 | 0.75 | THRB (0.37) | THRBTHRATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829142-B2 | Curable composition and process for production of organosilicon compound | TOAGOSEI CO., LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| EP-2270070-B1 | CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | TOAGOSEI CO LTD (JP) | 2014-07-30 | — | — | EP | disclosed |
| EP-2565217-B1 | Curable composition and process for production of organosilicon compound | TOAGOSEI CO LTD (JP) | 2014-05-14 | — | — | EP | disclosed |
| US-20130149455-A1 | CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | TOAGOSEI CO., LTD. (JP) | 2013-06-13 | — | — | US | disclosed |
| EP-2565217-A1 | Curable composition and process for production of organosilicon compound | TOAGOSEI CO., LTD. (JP) | 2013-03-06 | — | — | EP | disclosed |
| US-20110071255-A1 | CURABLE COMPOSITION AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | TOAGOSEI CO., LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
| EP-2270070-A1 | CURABLE COMPOSITION, AND PROCESS FOR PRODUCTION OF ORGANOSILICON COMPOUND | Toagosei Co., Ltd (JP) | 2011-01-05 | — | — | EP | disclosed |