Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 12/20 | 0.44 |
| ▸ | CA9 | Q16790 | 12/20 | 0.44 |
| ▸ | CA2 | P00918 | 10/20 | 0.44 |
| ▸ | CA7 | P43166 | 8/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19586659 | 0.80 | CA12 (0.43) | CA12CA9CA2CA7CA1 | |
| SCHEMBL1081860 | 0.80 | CA12 (0.50) | CA12CA9CA2CA7CA1 | |
| SCHEMBL10656700 | 0.78 | CA12 (0.49) | CA12CA9CA2CA7CA1 | |
| SCHEMBL5093607 | 0.78 | CA12 (0.45) | CA12CA9CA2CA7CA1 | |
| SCHEMBL6739070 | 0.77 | CA12 (0.41) | CA12CA9CA2CA7CA1 | |
| SCHEMBL7763714 | 0.73 | CA12 (0.44) | CA12CA9CA2CA7CA1 | |
| SCHEMBL8368219 | 0.73 | CA12 (0.38) | CA12CA9CA2CA7CA1 | |
| SCHEMBL3257815 | 0.72 | ALDH1A1 (0.54) | CA12CA9CA2CA7CA1 | |
| SCHEMBL2065981 | 0.71 | KDM4E (0.53) | KDM4EKMT2ALIG1ALDH1A1GAA | |
| Saccharin SCHEMBL789140 | 0.71 | CA12 (0.71) | CA12CA9CA2CA7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4701494-A | USING (METH) ACRYLOYL MONO- AND DISACCHARIDES, AN AZO FREE RADICAL CATALYST AND LIMITED AMOUNT OF MONOMER IN AQUEOUS SOLUTION | SHELL OIL COMPANY (US) | 1987-10-20 | — | — | US | claimed |
| US-5480790-A | PROTEINS ARE COVALENTLY BOUND TO POLYVINYLSACCHARIDE VIA A SACCHARIDE RESIDUE; PROTEIN-SACCHARIDE COMPLEXES SUCH AS DEXTRAN-T-40-ALPHA-GLUCOSIDASE AND GLUTAMATE DEHYDROGENASE POLYVINYLSACCHARIDE; ENZYME ANALYSIS; TEST KIT | BOEHRINGER MANNHEIM GMBH (DE) | 1996-01-02 | — | — | US | disclosed |