Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938291 | 0.71 | P2RY12 (0.53) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL31033502 | 0.69 | CYP2C19 (0.47) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL13125431 | 0.69 | HSP90AA1 (0.57) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL9621580 | 0.69 | P2RY12 (0.64) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL15993324 | 0.68 | MCOLN3 (0.41) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL22495571 | 0.68 | PTPN11 (0.48) | — | |
| SCHEMBL719388 | 0.68 | CYP2C19 (0.51) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL9224058 | 0.67 | KEAP1 (0.49) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL3386026 | 0.66 | KEAP1 (0.51) | CYP2C19P2RY12KEAP1NFE2L2KMT2A | |
| SCHEMBL9804556 | 0.66 | CYP2C19 (0.52) | CYP2C19P2RY12KEAP1NFE2L2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287691-A1 | Fungicidal control employing ester derivatives of 4,6-disubstituted 2-pyridinols | THE DOW CHEMICAL COMPANY (US) | 1988-10-26 | — | — | EP | claimed |
| US-4670045-A | FOR PLANTS | THE DOW CHEMICAL COMPANY (US) | 1987-06-02 | — | — | US | claimed |