Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985567 | 0.81 | CYP2C19 (0.46) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL10982599 | 0.80 | CYP2C19 (0.44) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL10719493 | 0.77 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL13125431 | 0.75 | HSP90AA1 (0.57) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL9621580 | 0.75 | P2RY12 (0.64) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL9938291 | 0.72 | P2RY12 (0.53) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL719388 | 0.71 | CYP2C19 (0.51) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL10993472 | 0.69 | CYP2C19 (0.48) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL31033502 | 0.68 | CYP2C19 (0.47) | CYP2C19P2RY12KEAP1NFE2L2MEN1 | |
| SCHEMBL9224058 | 0.68 | KEAP1 (0.49) | CYP2C19P2RY12KEAP1NFE2L2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270201-B1 | A METHOD FOR THE PREPARATION OF A 2,4-DIAMINO-3-OXY-PYRIMIDINE DERIVATIVE | ORION-YHTYMÀ OY (FI) | 1991-03-13 | — | — | EP | disclosed |
| US-4866174-A | Method for the preparation of a therapeutically active compound | FARMOS-YHTYMA OY (FI) | 1989-09-12 | — | — | US | disclosed |
| EP-0270201-A1 | A method for the preparation of a 2,4-diamino-3-oxy-pyrimidine derivative | ORION-YHTYMÀ OY (FI) | 1988-06-08 | — | — | EP | disclosed |