Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654711 | 0.94 | WNT3A (0.43) | GAAHPGDALDH1A1SLC22A12WNT3A | |
| SCHEMBL10653765 | 0.87 | ALDH1A1 (0.46) | GAAHPGDALDH1A1PGRKDM4E | |
| Hydrochloric Acid SCHEMBL10656938 | 0.86 | ALDH1A1 (0.45) | GAAHPGDALDH1A1PGRKDM4E | |
| SCHEMBL10658267 | 0.81 | KDM4E (0.48) | GAAALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3387533 | 0.81 | GAA (0.51) | GAAHPGDALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10715038 | 0.81 | ALDH1A1 (0.46) | GAAHPGDALDH1A1WNT3ATNKS2 | |
| Hydrochloric Acid SCHEMBL10654717 | 0.79 | ALDH1A1 (0.45) | GAAHPGDALDH1A1WNT3ATNKS2 | |
| SCHEMBL7797927 | 0.79 | GAA (0.50) | GAAALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8902778 | 0.76 | CYP3A4 (0.54) | GAAHPGDALDH1A1HTTMEN1 | |
| SCHEMBL11807436 | 0.76 | GAA (0.47) | GAAHPGDALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772630-A | ANTIDEPRESSANTS, ANTISCHIZOPHRENIA | CIBA-GEIGY CORP. (US) | 1988-09-20 | — | — | US | disclosed |