Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
| ▸ | ACR | P10323 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.60 |
| ▸ | RELA | Q04206 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MGLL | Q99685 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769419 | 1.00 | LMNA (0.62) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8023132 | 0.97 | LMNA (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11467054 | 0.97 | LMNA (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11763538 | 0.97 | LMNA (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14132233 | 0.96 | NPC1 (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8535590 | 0.96 | NPC1 (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5881164 | 0.96 | LMNA (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL13384900 | 0.96 | LMNA (0.58) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11459004 | 0.96 | NPC1 (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5348247 | 0.96 | NPC1 (0.67) | LMNANPC1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52017441-A | — | — | None | — | — | JP | disclosed |
| US-4751017-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-06-14 | — | — | US | disclosed |
| JP-S5217441-A | PROCESS FOR PREPARATION OF P-CYANOPHENYLESTER OF 4-SUBSTITUTED- BENZOI C ACID | CHISSO CORP | 1977-02-09 | — | — | JP | disclosed |
| US-3977768-A | Nematic liquid crystal compositions | DAI NIPPON TORYO KAUBSHIKI KAISHA (JA) | 1976-08-31 | — | — | US | disclosed |