Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052910 | 0.76 | GSR (0.48) | MEN1KMT2AGRIK1GRIK2SLC1A2 | |
| SCHEMBL10052911 | 0.76 | GSR (0.48) | MEN1KMT2AGRIK1GRIK2SLC1A2 | |
| SCHEMBL2398354 | 0.74 | ALDH1A1 (0.56) | MEN1KMT2ATDP1 | |
| SCHEMBL10932413 | 0.74 | MAPK1 (0.36) | TDP1MAPK1 | |
| SCHEMBL13702970 | 0.73 | LMNA (0.42) | MEN1KMT2AMAPK1 | |
| SCHEMBL21577238 | 0.72 | TRPV1 (0.38) | MAPK1 | |
| SCHEMBL28511943 | 0.72 | GRIK1 (0.56) | MEN1KMT2ACHRM1AKR1A1CHRM3 | |
| SCHEMBL5515553 | 0.72 | CHRM1 (0.61) | MEN1GAAKMT2ACHRM1AKR1A1 | |
| SCHEMBL24627511 | 0.71 | LMNA (0.40) | MEN1KMT2AMAPK1 | |
| SCHEMBL13702974 | 0.71 | LMNA (0.40) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725620-A | 2H-pyran-2,6-(3H)-dione derivatives with anti-allergic activity | ALLERGAN, INC. (US) | 1988-02-16 | — | — | US | disclosed |