Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10657254 | 1.00 | MAPT (0.47) | MAPTLMNATP53PRKD3PRKCG | |
| SCHEMBL10657244 | 1.00 | MAPT (0.47) | MAPTLMNATP53PRKD3PRKCG | |
| SCHEMBL10657252 | 1.00 | MAPT (0.47) | MAPTLMNATP53PRKD3PRKCG | |
| SCHEMBL11372817 | 0.83 | LMNA (0.56) | MAPTLMNAMEN1KMT2APTPN1 | |
| SCHEMBL17681484 | 0.81 | CYP1A2 (0.46) | MAPTLMNATP53CYP1A2LSS | |
| SCHEMBL10485974 | 0.79 | CYP1A2 (0.52) | LMNATP53CYP1A2LSSMEN1 | |
| SCHEMBL10706195 | 0.79 | CYP1A2 (0.52) | LMNATP53CYP1A2LSSMEN1 | |
| SCHEMBL8216620 | 0.79 | CYP1A2 (0.52) | LMNATP53CYP1A2LSSMEN1 | |
| SCHEMBL10486024 | 0.79 | CYP1A2 (0.52) | LMNATP53CYP1A2LSSMEN1 | |
| SCHEMBL10702696 | 0.79 | CYP1A2 (0.52) | LMNATP53CYP1A2LSSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257048-A1 | OPTICALLY ACTIVE COMPOUNDS. | MERCK PATENT GMBH (DE) | 1988-03-02 | — | — | EP | disclosed |
| WO-1987005018-A2 | OPTICALLY ACTIVE COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |