SCHEMBL106573

SCHEMBL106573

Cn1cnc2c(N)ncnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 12/20 1.00
ADORA1 P30542 8/20 1.00
ADORA2B P29275 3/20 0.61
PI4KA P42356 9/20 0.59
PI4K2B Q8TCG2 9/20 0.59
PI4K2A Q9BTU6 9/20 0.59
PI4KB Q9UBF8 9/20 0.59
YTHDC1 Q96MU7 1/20 0.56
CDK1 P06493 1/20 0.55
EGFR P00533 1/20 0.51
ADORA3 P0DMS8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7147821 0.98 ADORA2A (0.96) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL7140260 0.98 ADORA2A (0.96) ADORA2AADORA1ADORA2BPI4KAPI4K2B
Furan SCHEMBL28428657 0.88 ADORA2A (0.77) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL4661802 0.81 ADORA2A (0.65) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL580610 0.78 ADORA2A (0.64) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL11222112 0.78 ADORA2A (0.80) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL28413958 0.77 ADORA2A (0.62) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL441875 0.77 ADORA1 (0.62) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL667204 0.77 ADORA2A (0.62) ADORA2AADORA1ADORA2BPI4KAPI4K2B
SCHEMBL6883849 0.76 ADORA2A (0.61) ADORA2AADORA1ADORA2BPI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4388 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137576-A1 MULTIPLE SPECIFIC ANTIBODIES TARGETING CD19, CD20, AND/OR CD47 NUTCRACKER THERAPEUTICS, INC. (US) 2025-06-26 WO claimed
CN-120130364-A Method for inducing and regenerating seedlings by using black lattice callus 广西壮族自治区林业科学研究院 2025-06-13 CN claimed
CN-119639754-A MRNA and synthesis method thereof, mRNA vaccine, capped RNA and in vitro transcription reaction liquid 上海兆维医药科技有限公司 2025-03-18 CN claimed
WO-2025041085-A1 DUAL NUCLEASE SYSTEMS FOR GENE EDITING, METHODS OF PRODUCING AND USING SAME SPECIFIC BIOLOGICS INC. (CA) 2025-02-27 WO claimed
CN-119404296-A Semiconductor processing liquid, method for processing object to be processed, and method for manufacturing electronic device 富士胶片株式会社 2025-02-07 CN claimed
CN-118108781-A Capped polynucleotide, capped mRNA, capped composition, pharmaceutical protein, preparation method and application of capped polynucleotide and capped mRNA, pharmaceutical preparation 上海兆维科技发展有限公司 2024-05-31 CN claimed
US-20240158433-A1 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TRILINK BIOTECHNOLOGIES, LLC (US) 2024-05-16 US claimed
US-20240140982-A1 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5'-CAPPED RNAS TRILINK BIOTECHNOLOGIES, LLC (US) 2024-05-02 US claimed
WO-2024064369-A1 METHODS FOR AMPLIFYING NUCLEIC ACIDS FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2024-03-28 WO claimed
EP-4104687-B1 COMPOSITIONS AND METHODS FOR SYNTHESIZING 5 -CAPPED RNAS TRILINK BIOTECHNOLOGIES LLC (US) 2024-01-31 EP claimed
EP-0846772-A1 Multifunctional ligand system for cell-specific transfer of nucleic acid HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-10 EP claimed
US-5703224-A Antiviral c-nucleoside derivatives NIPPON SHINYAKU CO. LTD. (JP) 1997-12-30 US claimed
US-5643744-A CONDENSATION OF AMINO ACID AND A NUCLEIC ACID ADAPTER IN PRESENCE OF RIBOSOMES AND AROMATIC TERTIARY AMINE BUT NO ENERGY SOURCE SUCH AS ATP OR GTP SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-01 US claimed
WO-1997012993-A1 MISMATCH REPAIR DETECTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-04-10 WO claimed
EP-0755254-A1 PREVENTION AND TREATMENT OF ISCHEMIA-REPERFUSION AND ENDOTOXIN-RELATED INJURY USING ADENOSINE AND PURINO RECEPTOR ANTAGONISTS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1997-01-29 EP claimed
EP-0733630-A1 NUCLEOSIDE DERIVATIVE NIPPON SHINYAKU COMPANY, LIMITED (JP) 1996-09-25 EP claimed
WO-1995026728-A1 PREVENTION AND TREATMENT OF ISCHEMIA-REPERFUSION AND ENDOTOXIN-RELATED INJURY USING ADENOSINE AND PURINO RECEPTOR ANTAGONISTS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1995-10-12 WO claimed
WO-1995011685-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1995-05-04 WO claimed
EP-0646648-A1 Method for producing polypeptide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-04-05 EP claimed
WO-1991016333-A1 2',3'-DIDEOXY-4'-THIORIBONUCLEOSIDES AS ANTIVIRAL AGENTS SOUTHERN RESEARCH INSTITUTE (US) 1991-10-31 WO claimed