SCHEMBL667204

SCHEMBL667204

Nc1ncnc2c1ncn2N

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 13/20 0.62
ADORA1 P30542 9/20 0.62
PI4KA P42356 10/20 0.56
PI4K2B Q8TCG2 10/20 0.56
PI4K2A Q9BTU6 10/20 0.56
PI4KB Q9UBF8 10/20 0.56
ADORA2B P29275 4/20 0.56
EGFR P00533 1/20 0.53
ADORA3 P0DMS8 2/20 0.51
GSK3B P49841 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL580610 0.80 ADORA2A (0.64) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL28413958 0.78 ADORA2A (0.62) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL8069211 0.77 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL2342091 0.77 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL16949893 0.77 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL9074153 0.77 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL11908593 0.77 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL1357265 0.77 ADORA2A (0.60) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL1868819 0.77 FDPS (0.44) ADORA2AADORA1PI4KAPI4K2BPI4K2A
SCHEMBL16949944 0.77 ADORA2A (0.37) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 841 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108605844-A A kind of method that Jiading garlic stem apex detoxic seedling forms detoxification clove 上海惠和种业有限公司 2018-10-02 CN claimed
CN-105669751-B The preparation of acyclonucleosides acid phosphoramide types compound and its salt and the application in anti-virus aspect 洛阳聚慧医药科技有限公司 2018-09-21 CN claimed
CN-106565785-A Nucleoside phosphoramidate type compound with HBV/HIV resistance activity and salt and application of nucleoside phosphoramidate type compound 周雨恬 2017-04-19 CN claimed
CN-105669751-A Preparation of non-cyclic nucleotide phosphoamides and salts thereof and application of non-cyclic nucleotide phosphoamides and salts thereof in aspect of antivirus 洛阳聚慧医药科技有限公司 2016-06-15 CN claimed
US-8039611-B2 2′-hydroxyl group-modified ribonucleoside derivatives TOKYO INSTITUTE OF TECHNOLOGY (JP) 2011-10-18 US claimed
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
CN-122038302-A Modified T cells and methods of making and using the same 哈佛学院校长同事会 2026-05-15 CN disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 US disclosed
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-23 US disclosed
EP-0689610-A1 DNA SEQUENCING BY MASS SPECTROMETRY VIA EXONUCLEASE DEGRADATION SEQUENOM, INC. (US) 1996-01-03 EP disclosed
EP-0684979-A1 LUBRICANT COMPOSITIONS CONTAINING COMPLEXES OF ALKOXYLATED AMINE, ACID, AND ADENINE. EXXON RESEARCH ENGINEERING CO (US) 1995-12-06 EP disclosed
EP-0670897-A1 ANTISENSE OLIGONUCLEOTIDE INHIBITION OF THE ras GENE ISIS PHARMACEUTICALS, INC. (US) 1995-09-13 EP disclosed
WO-1994021822-A1 DNA SEQUENCING BY MASS SPECTROMETRY VIA EXONUCLEASE DEGRADATION SEQUENOM, INC. (US) 1994-09-29 WO disclosed
WO-1994019437-A1 LUBRICANT COMPOSITIONS CONTAINING COMPLEXES OF ALKOXYLATED AMINE, ACID, AND ADENINE EXXON RESEARCH & ENGINEERING COMPANY (US) 1994-09-01 WO disclosed
WO-1994008003-A1 ANTISENSE OLIGONUCLEOTIDE INHIBITION OF THE ras GENE ISIS PHARMACEUTICALS, INC. (US) 1994-04-14 WO disclosed
US-5290460-A Friction resistant compounds EXXON RESEARCH & ENGINEERING CO. (US) 1994-03-01 US disclosed
US-4704193-A Covalently coupled cofactor modified electrodes and methods of synthesis and use GTE LABORATORIES INCORPORATED (US) 1987-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD ADORA2A 276/4885ADORA1 181/4885PI4KA 487/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 ADORA2A 828/4885ADORA1 1014/4885PI4KA 1526/4885
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES RNMT, METTL16, NSUN2 ADORA2A 2246/4885ADORA1 1287/4885PI4KA 2441/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT ADORA2A 3858/4885ADORA1 3856/4885PI4KA 1271/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 ADORA2A 2670/4885ADORA1 2796/4885PI4KA 4408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.