Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.65 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | PI4KA | P42356 | 9/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 9/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 9/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106573 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL7140260 | 0.79 | ADORA2A (0.96) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL7147821 | 0.79 | ADORA2A (0.96) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL1065184 | 0.78 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL19929 | 0.77 | — | — | |
| SCHEMBL27952255 | 0.77 | PIK3CB (0.41) | PI4KAPI4KBLMNA | |
| Iodide SCHEMBL29172953 | 0.75 | PIK3CB (0.40) | PI4KAPI4KBLMNA | |
| Hydrochloric Acid SCHEMBL6853659 | 0.75 | PIK3CB (0.40) | PI4KAPI4KBLMNA | |
| Adenine SCHEMBL28547223 | 0.74 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Furan SCHEMBL28428657 | 0.71 | ADORA2A (0.77) | ADORA2AADORA1ADORA2BPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004847-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | Pentabase Aps (DK) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007104318-A2 | OLIGONUCLEOTIDES COMPRISING SIGNALLING PAIRS AND HYDROPHOBIC NUCLEOTIDES, STEMLESS BEACONS, FOR DETECTION OF NUCLEIC ACIDS, METHYLATION STATUS AND MUTANTS OF NUCLEIC ACIDS | PENTABASE APS (DK) | 2007-09-20 | — | — | WO | disclosed |