SCHEMBL10657397

SCHEMBL10657397

C=C(C)C(=O)OC(C)OC(CC)[Si](C)(C)OCC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1551132 0.86 THRB (0.37) TSHRTHRB
SCHEMBL7866733 0.82 TSHR (0.36) TSHRTHRB
SCHEMBL10663718 0.82 TSHR (0.32) TSHR
SCHEMBL10885738 0.80 TSHR (0.37) TSHRTHRB
SCHEMBL10889685 0.79 TSHR (0.34) TSHR
SCHEMBL2138112 0.79 TSHR (0.34) TSHR
SCHEMBL10659040 0.79 TSHR (0.36) TSHRTHRB
SCHEMBL16537597 0.78 TSHR (0.40) TSHRTHRB
SCHEMBL16537348 0.77 ALDH1A1 (0.35) TSHRTHRB
SCHEMBL2363206 0.76 THRB (0.37) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed