SCHEMBL10657484

SCHEMBL10657484

COC(CCl)Oc1ccccc1N(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 4/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
PAX8 Q06710 2/20 0.34
TLR9 Q9NR96 1/20 0.34
MEN1 O00255 3/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.33
JAK2 O60674 1/20 0.33
MITF O75030 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
POLB P06746 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11509644 0.89 TSPO (0.43) TSPOL3MBTL1KMT2AALDH1A1KDM4E
SCHEMBL11852293 0.78 TSPO (0.41) TSPOL3MBTL1KMT2AALDH1A1KDM4E
SCHEMBL947357 0.77 ALDH1A1 (0.50) TSPOKMT2AALDH1A1KDM4EMEN1
SCHEMBL11509645 0.76 TSPO (0.46) TSPOKMT2AALDH1A1KDM4EMEN1
SCHEMBL11848080 0.76 KMT2A (0.39) TSPOKMT2AALDH1A1KDM4EMEN1
SCHEMBL8779753 0.75 TSPO (0.53) TSPOKMT2AALDH1A1KDM4EPAX8
SCHEMBL11272508 0.75 MEN1 (0.35) KMT2AALDH1A1KDM4EMEN1CRHBP
SCHEMBL11848581 0.74 TSPO (0.43) TSPOL3MBTL1KMT2AALDH1A1KDM4E
SCHEMBL11854407 0.73 TSPO (0.37) TSPOALDH1A1KDM4ENPC1SLC6A9
SCHEMBL11142667 0.72 TP53 (0.48) L3MBTL1KMT2AALDH1A1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63238005-A None JP disclosed
JP-S63238005-A MOLLUSCICIDAL METHOD BY 2-(2-CHLORO-1- METHOXY-ETHOXY)-PHENYL-METHYLCARBAMATE AND MOLLUSCICIDE BASF AG 1988-10-04 JP disclosed
EP-0033098-B1 N-METHYL-N-SILYL-CARBAMATES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES BASF Aktiengesellschaft (DE) 1983-11-23 EP disclosed
US-4360517-A INSECTICIDES, MITICIDES, AND NEMATOCIDES BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed
EP-0033098-A2 N-methyl-N-silyl-carbamates, processes for their preparation and their use as pesticides BASF Aktiengesellschaft (DE) 1981-08-05 EP disclosed