Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | GLB1 | P16278 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10665470 | 0.94 | GNAI3 (0.52) | GNAI3GNAO1GNAI1DRD3SIGMAR1 | |
| SCHEMBL10659794 | 0.92 | GNAI3 (0.55) | GNAI3GNAO1GNAI1SIGMAR1KDM4E | |
| SCHEMBL15590758 | 0.88 | GNAI3 (0.37) | GNAI3GNAO1GNAI1DRD2DRD3 | |
| SCHEMBL10662555 | 0.86 | DRD2 (0.44) | GNAI3GNAO1GNAI1DRD2DRD3 | |
| SCHEMBL2318272 | 0.81 | GNAI3 (0.58) | GNAI3GNAO1GNAI1DRD2DRD3 | |
| SCHEMBL1537447 | 0.81 | — | — | |
| SCHEMBL18538874 | 0.81 | GNAI3 (0.58) | GNAI3GNAO1GNAI1DRD2DRD3 | |
| SCHEMBL1043894 | 0.81 | GNAI3 (0.58) | GNAI3GNAO1GNAI1DRD2DRD3 | |
| SCHEMBL15590864 | 0.80 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SIGMAR1KDM4E | |
| SCHEMBL16487995 | 0.80 | GNAI3 (0.47) | GNAI3GNAO1GNAI1SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4747953-A | Composite membranes based on interpenetrating polymer networks | ALLIED CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |