Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Dodecylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.68 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.60 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.60 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.60 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.56 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecylamine SCHEMBL5885986 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Decylamine SCHEMBL2745579 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Tetradecylamine SCHEMBL7641962 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL7118141 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL3406817 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL23525472 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octadecylamine SCHEMBL5885991 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hexadecylamine SCHEMBL8378529 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL9011419 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL10967256 | 1.00 | DNM1 (0.68) | DNM1MEN1KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4735971-A | CONTAINING ISOPROPENYL OXYSILYL- AND MERCAPTOALKYL GROUPS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-04-05 | — | — | US | claimed |